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What causes bone cancer?

What causes bone cancer?

Bone cancer is caused by a problem with the cells that make bone. More than 2,000 people are diagnosed in the United States each year with a bone tumor. Bone tumors occur most commonly in children and adolescents and are less common in older adults. Cancer involving the bone in older adults is most commonly the result of metastatic spread …

Definition of Chordoma

Definition of Chordoma

Chordoma: A form of bone cancer that usually starts in the lower spinal column.
Chordoma is a rare slow-growing malignant neoplasm thought to arise from cellular remnants of the notochord. The evidence for this is the location of the tumors (along the neuraxis), the similar immunohistochemical staining patterns, and the demonstration that notochordal cells are preferentially left behind in the clivus …

Definition of Fibrosarcoma

Definition of Fibrosarcoma

Fibrosarcoma: A malignant tumor that begins in fibrous connective tissue at the ends of the arm or leg bones and may spread to surrounding soft tissue. Fibrosarcoma is the most common soft tissue sarcoma found in children under one year of age. It presents as a rapidly growing mass at birth or early infancy. Fibrosarcoma can also occur in older …

Definition of Chondrosarcoma

Definition of Chondrosarcoma

Chondrosarcoma: A malignant tumor that forms in cartilage cells (chondroplasts) and that produces cartilage matrix. Chondrosarcoma can be primary or secondary. Primary chondrosarcoma forms in bone and is found in children. Secondary chondrosarcoma arises from preexisting benign defects of cartilage (such as an osteochondroma or enchondroma), usually after age 40. Treatment is mainly by surgery.
Source : http://www.medicinenet.com/

Definition of Ewing sarcoma

Definition of Ewing sarcoma

Ewing sarcoma: A type of bone tumor that occurs in children and adolescents, most often in the large bones of the arms and legs and the flat bones of the pelvis, spine and ribs. The tumor is caused by a chromosome abnormality, called a translocation (an exchange of material), most commonly between chromosomes 11 and 22 that occurs by chance …

Definition of Osteosarcoma

Definition of Osteosarcoma

Osteosarcoma: A cancer of the bone that occurs predominantly in adolescents and young adults. It accounts for 5 percent of cancer in children.
The site of the osteosarcoma is the most important prognostic factor since it determines whether the tumor can be surgically removed. Osteosarcoma is very resistant to radiation therapy. In children and adolescents, half of osteosarcomas arise from the …